H E A L T H C A R E

How to Use Japanese Pharmacies & Drugstores: OTC Medicine, Prescriptions & Tax-Free

Drugstore vs prescription pharmacy, OTC medicine categories, what you can't buy without a prescription, tax-free shopping at Matsumoto Kiyoshi, and the 4-day prescription rule.

How to Use Japanese Pharmacies & Drugstores: OTC Medicine, Prescriptions & Tax-Free

Quick Answer

  • Headache, cold, stomach? Walk into any Matsumoto Kiyoshi, Welcia, Tsuruha, or Sundrug. Point at where it hurts — staff will recommend medicine. No prescription needed for most OTC drugs.
  • Loxonin S (Japan’s best painkiller) is behind the counter — ask the pharmacist: 「ロキソニンSをください」 (Rokisonin S o kudasai).
  • Tax-free shopping available at most tourist-area drugstores (¥5,000+ purchase). Bring your passport.
  • Got a prescription? Take it to a 薬局 (yakkyoku) within 4 days or it expires. There’s usually one right next to the clinic.
  • Can’t find your home medication? Brand names differ. Bring the generic name (e.g., “ibuprofen” not “Advil”) and show it to the pharmacist.
  • Prescriptions: Take your 処方箋 + insurance card to any 薬局. You pay 30% of drug costs. Ask for ジェネリック (generic) to save money.
  • Get an お薬手帳 (medicine notebook) — free at any pharmacy. It tracks all prescriptions and catches drug interactions. Bring it to every appointment.
  • Prescriptions expire in 4 days (including issue date). Don’t wait.
  • Regular medication? Ask your doctor for a 90-day prescription (長期処方) to reduce clinic visits.
  • Loxonin S and other strong OTC meds are Class 1 (第1類) — behind the counter. Ask the pharmacist.

What This Guide Covers

You’ll be able to:

  • Buy the right OTC medicine for common traveler ailments
  • Fill a prescription at a Japanese pharmacy
  • Understand Japan’s 3-tier OTC medicine classification
  • Get tax-free discounts at drugstores
  • Navigate a pharmacy without speaking Japanese

⏱️ Time: Drugstore purchase: 5 minutes. Prescription fill: 10–20 minutes.

💰 Cost: OTC medicine ¥500–¥2,000. Prescription with insurance: 30% of drug cost.

⚠️ Watch out for:

  • Prescription expires in 4 days — don’t procrastinate
  • Loxonin S requires pharmacist consultation (you can’t just grab it)
  • Codeine and pseudoephedrine have stricter rules than in your home country

Drugstore vs Prescription Pharmacy: Two Different Places

A brightly lit Japanese drugstore with shelves of medicine and cosmetics

This confuses almost every foreigner. Japan has two types of places that sell medicine, and they serve completely different purposes:

Drugstore (ドラッグストア)Prescription Pharmacy (調剤薬局)
What it isRetail store. Think CVS/Boots mixed with a cosmetics shop.Small pharmacy, usually next to a clinic or hospital.
What it sellsOTC medicine, cosmetics, snacks, drinks, household itemsPrescription medicine only (plus some OTC)
Prescription needed?No (for OTC items)Yes
ExamplesMatsumoto Kiyoshi, Welcia, Tsuruha, Sundrug, Cocokara FineThe small 「薬局」 next to your clinic
Tax-free?Yes (at tourist locations, ¥5,000+ purchase)No
Hours9:00–22:00 (some 24/7)Usually 9:00–18:00, closed Sundays

Rule of thumb: For a headache, cold, or stomach trouble → drugstore. For medicine a doctor prescribed → prescription pharmacy (薬局).


OTC Medicine: What to Buy for Common Problems

Japan’s OTC Medicine Classification

Japan classifies OTC medicines into 3 categories based on risk. This matters because you can’t just grab everything off the shelf:

CategoryRisk LevelHow to BuyExamples
第1類 (Class 1)Highest risk OTCMust consult pharmacist. Behind the counter.Loxonin S, Gaster 10, some allergy meds
第2類 (Class 2)Moderate riskOn the shelf, but pharmacist will explain if asked.Bufferin, Pabron, Eve A
第3類 (Class 3)Lowest riskGrab and go. No consultation needed.Vitamin supplements, eye drops, throat lozenges

The catch with Class 1: You’ll see an empty box on the shelf. Take it to the counter, and the pharmacist will give you the actual medicine after a brief consultation. If no pharmacist is on duty (some drugstores in late hours), they cannot sell Class 1 items. Look for the 「薬剤師常駐」 sign.

The Tourist Medicine Kit: What to Buy

ProblemMedicineJapanese NameCategoryPriceNotes
Headache/painLoxonin SロキソニンSClass 1~¥700Japan’s most popular painkiller. Ask at counter.
Headache (milder)Bufferin AバファリンAClass 2~¥600Aspirin-based. On the shelf.
Headache (ibuprofen)Eve AイブAClass 2~¥600Ibuprofen-based. On the shelf.
Cold/fluPabron Gold AパブロンゴールドAClass 2~¥1,500All-in-one cold medicine. Very popular.
Stomach acheOhta’s Isan太田胃散Class 2~¥700Powder form. Classic Japanese stomach remedy.
DiarrheaSeirogan正露丸Class 2~¥800Strong herbal remedy. Distinctive smell. Works.
AllergiesAllegra FXアレグラFXClass 1~¥1,400Same as US Allegra. Ask at counter.
Muscle painSalonpasサロンパスClass 3~¥500Pain relief patches. Grab and go.
Sore throatLulu Throat LozengesルルのどスプレーClass 3~¥600Spray or lozenges.
Eye dropsSante FX NeoサンテFX ネオClass 2~¥500Cooling eye drops. Very refreshing.

How to Ask for Medicine (Without Speaking Japanese)

Method 1: Point at it. Walk to the medicine section and point at the box. Staff will nod and ring it up. For Class 1 items (empty boxes on shelf), take the box to the pharmacist counter.

Method 2: Describe your symptom. Point to where it hurts and say:

「ここが痛いです」(Koko ga itai desu — It hurts here) 「頭が痛いです」(Atama ga itai desu — Headache) 「お腹が痛いです」(Onaka ga itai desu — Stomach ache) 「熱があります」(Netsu ga arimasu — I have a fever) 「風邪です」(Kaze desu — I have a cold)

The pharmacist will walk you to the right medicine.

Method 3: Show the English name on your phone. Type “ibuprofen” or “antihistamine” into Google Translate (English → Japanese) and show it to the pharmacist. They’ll find the equivalent.


Filling a Prescription: Step by Step

A small Japanese prescription pharmacy next to a clinic

After seeing a doctor in Japan, you don’t get medicine at the clinic. You get a piece of paper (処方箋, shohousen) and take it to a pharmacy.

The Process

Step 1: Leave the clinic with your prescription paper.

Step 2: Walk to the nearest pharmacy (薬局). There’s almost always one within 30 seconds of any clinic — look for the green cross or 「薬局」 sign.

Step 3: Hand over:

  • The prescription (処方箋)
  • Your insurance card (保険証) — if you have one

Step 4: The pharmacist will say:

「お薬手帳はお持ちですか?」 (Okusuri techō wa omochi desu ka? — Do you have a medicine notebook?)

If you don’t have one, say: 「ありません」(Arimasen — No, I don’t). They’ll give you a free one.

Step 5: Wait 10–20 minutes. The pharmacist prepares your medicine.

Step 6: The pharmacist explains dosage:

「1日3回、食後に飲んでください」 (Ichinichi san-kai, shokugo ni nonde kudasai — Take 3 times a day, after meals)

Common dosage instructions:

JapaneseMeaning
1日1回Once a day
1日2回Twice a day
1日3回Three times a day
食前Before meals
食後After meals
寝る前Before bed
1回1錠1 tablet per dose
1回2錠2 tablets per dose

Step 7: Pay. With insurance: 30% of the drug cost. Without insurance: full price.

The 4-Day Rule

Prescriptions expire 4 days after issue (including the day of issue). Get a prescription on Monday? It expires Thursday. Miss the deadline? You’ll need a new clinic visit and a new prescription. Don’t put it off.

Save Money: Ask for Generics

Say this at the pharmacy counter:

「ジェネリックでお願いします」 (Jenerikku de onegai shimasu — Generic, please)

Generic drugs (後発医薬品) are 30–80% cheaper than brand-name drugs and equally effective. The pharmacist must legally offer them if available.


The Pitfall: Medicine You Can’t Buy in Japan

Some medicines that are available OTC in your home country require a prescription or are banned in Japan:

MedicineStatus in JapanWhat to Do
Adderall, Ritalin (ADHD)Banned. Amphetamine/methylphenidate are controlled.Leave at home. Consult your doctor for alternatives before traveling.
Codeine (strong)Prescription onlyAvailable in some OTC cold meds in tiny doses, but strong codeine needs a prescription.
Pseudoephedrine (Sudafed)RestrictedAvailable in very low doses in some cold meds. High-dose Sudafed doesn’t exist OTC in Japan.
MelatoninNot sold OTCBring from home (personal use, reasonable quantity is OK).
Birth control pillPrescription onlySee a gynecologist in Japan. Not available at drugstores.
Ibuprofen (high dose 400mg+)Prescription onlyOTC ibuprofen in Japan is lower dose (150–200mg). For higher dose, see a doctor.

If you take regular prescription medication: Bring enough supply for your trip, plus a letter from your doctor in English stating the medication name (generic), dosage, and reason. Check Japan’s MHLW Controlled Substances List before traveling.


Tax-Free Shopping at Drugstores

Tax-free counter at a Japanese drugstore

Major drugstore chains offer tax-free shopping (消費税10% off) for tourists:

Requirements:

  • Non-resident status (tourist visa)
  • Passport (they’ll attach a record to it)
  • Minimum purchase: ¥5,000 (excluding tax) in one store, one visit
  • Note: Starting November 2026, Japan’s tax-free system changes to a refund-at-departure model. Until then, the current at-register exemption applies.

Drugstores with tax-free counters in tourist areas:

ChainLocationsTax-Free?English Staff?
Matsumoto KiyoshiShibuya, Shinjuku, Ginza, AsakusaYesYes (tourist stores)
WelciaNationwide (3,000+ stores)Some locationsLimited
TsuruhaNationwideSome locationsLimited
SundrugShinjuku, Shibuya, UenoYesSome stores
Cocokara FineMajor stationsSome locationsLimited
Don QuijoteTourist hotspotsYesYes

Pro tip: Matsumoto Kiyoshi in Shibuya Center-gai and Shinjuku Kabukicho are the most tourist-friendly — multilingual staff, English product labels, and tax-free counters. They also offer additional coupon discounts (3–7% off) if you show the coupon from their website or tourist apps.

What to stock up on: Japanese sunscreen (Anessa, Biore UV), sheet masks (LuLuLun), lip balm (Mentholatum), Salonpas patches, eye drops (Rohto). These are significantly cheaper than back home.


The Okusuri Techo: Your Free Medicine Tracker

The お薬手帳 (Okusuri Techō, medicine notebook) is a free booklet you get at any pharmacy. Every time you fill a prescription, the pharmacist adds a sticker with:

  • Drug name
  • Dosage
  • Date prescribed
  • Prescribing doctor

Why it matters:

  • Prevents dangerous drug interactions
  • Useful in emergencies (doctors can see your medication history instantly)
  • Required for accurate prescriptions if you switch clinics
  • Saves you money: Having an okusuri techo and using the same pharmacy earns a small discount on dispensing fees.

Get one on your first pharmacy visit. If you forget it, the pharmacist still fills your prescription — they’ll give you stickers to paste in later.


When Things Don’t Work Out

ProblemCauseSolution
Pharmacy says "no pharmacist on duty" Late hours. Some drugstores keep selling Class 2/3 but can't sell Class 1 without a pharmacist. Come back during business hours (9:00–18:00), or find a larger drugstore with 「薬剤師常駐」 sign.
Prescription expired (past 4 days) You waited too long Go back to the clinic for a new prescription. You'll pay the consultation fee again.
Can't find your home medication Brand names differ between countries Show the generic (chemical) name to the pharmacist. Google Translate works. Or visit an English-speaking clinic — the doctor can prescribe the Japanese equivalent.
Medicine is too expensive without insurance Some prescribed drugs are costly at 100% price Ask for ジェネリック (generic). Or ask the doctor for a cheaper alternative. Keep receipts for travel insurance claims.
Pharmacist doesn't understand English Most pharmacists speak limited English Use Google Translate camera mode to scan medicine boxes. Or show symptoms in Japanese on your phone.

FAQ

Q: Can I buy antibiotics without a prescription in Japan?

A: No. Antibiotics require a prescription in Japan — no exceptions. This is different from some countries where antibiotics are available OTC. If you think you need antibiotics, you must see a doctor first.


Q: Is Tylenol/Paracetamol available in Japan?

A: Yes, but under different names. Look for Calonal (カロナール) at a pharmacy, or Tylenol A (タイレノールA) at drugstores. The active ingredient is acetaminophen (アセトアミノフェン), same as Tylenol/Paracetamol. Class 2 — on the shelf.


Q: Can I bring my own prescription medication into Japan?

A: Yes, for personal use — up to 1 month’s supply without special permission, up to 2 months’ supply with a Yakkan Shoumei (import certificate from MHLW). Some substances are completely banned (amphetamines, certain opioids). Check the MHLW website before you travel. Carry a doctor’s letter in English.


Q: Are drugstores open late?

A: Most chain drugstores close at 21:00–22:00. Some Welcia and Don Quijote locations are open 24 hours. Convenience stores (7-Eleven, Lawson, FamilyMart) sell very basic medicine (band-aids, throat lozenges, mild cold medicine) 24/7 — but the selection is limited.


Q: How do I ask the pharmacist to recommend something?

A: Point to where it hurts and say:

「おすすめの薬はありますか?」 (Osusume no kusuri wa arimasu ka? — Do you recommend any medicine?)

Or simply:

「風邪の薬をください」 (Kaze no kusuri o kudasai — Cold medicine, please) 「頭痛薬をください」 (Zutsū-yaku o kudasai — Headache medicine, please) 「胃薬をください」 (Igusuri o kudasai — Stomach medicine, please)



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